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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1345977
Species: Homo sapiens
RGD Object: Gene
Symbol: CETP
Name: cholesteryl ester transfer protein
Acc ID: CHEBI:4911
Term: etoposide
Definition: A furonaphthodioxole that has formula C29H32O13.
Chemical ID: MESH:D005047
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CETPincreases expressionEXP 6480464CTDEtoposide results in increased expression of CETP mRNA; Etoposide results in increased expression of CETP proteinPMID:25914138
CETPmultiple interactionsEXP 6480464CTD[Tretinoin co-treated with Etoposide] results in increased expression of CETP mRNA; Etoposide promotes the reaction [NR1H2 protein results in increased expression of CETP mRNA]; Etoposide promotes the reaction [NR1H3 protein results in increased expression of CETP mRNA]; Etoposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]; NR1H2 mutant form inhibits the reaction [Etoposide results in increased expression of CETP mRNA]; NR1H3 mutant form inhibits the reaction [Etoposide results in increased expression of CETP mRNA]; Tretinoin promotes the reaction [Etoposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]]; Tretinoin promotes the reaction [Etoposide results in increased expression of CETP protein]PMID:25914138
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