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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352097
Species: Homo sapiens
RGD Object: Gene
Symbol: POMC
Name: proopiomelanocortin
Acc ID: CHEBI:49108
Term: dopachrome
Definition: An orthoquinone that has formula C9H7NO4.
Chemical ID: MESH:C001123
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
POMCmultiple interactionsISOPomc (Mus musculus)6480464CTD[POMC protein modified form results in increased activity of TYR protein] which results in increased chemical synthesis of dopachrome; Quercetin analog inhibits the reaction [[POMC protein modified form results in increased activity of TYR protein] which results in increased chemical synthesis of dopachrome]PMID:26586997
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