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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61859
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gabra5
Name: gamma-aminobutyric acid type A receptor subunit alpha 5
Acc ID: CHEBI:4910
Term: etomidate
Definition: The ethyl ester of 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylic acid. It is an intravenous general anaesthetic with no analgesic activity.
Chemical ID: MESH:D005045
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gabra5affects response to substanceISOGabra5 (Mus musculus)6480464CTDGABRA5 protein affects the susceptibility to EtomidatePMID:16597725
Gabra5multiple interactionsISOGabra5 (Mus musculus)6480464CTDEtomidate binds to and results in increased activity of GABRA5 proteinPMID:16597725
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