Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735225
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Serping1
Name: serpin family G member 1
Acc ID: CHEBI:4903
Term: 17alpha-ethynylestradiol
Definition: A 3-hydroxy steroid that is estradiol substituted by a ethynyl group at position 17. It is a xenoestrogen synthesized from estradiol and has been shown to exhibit high estrogenic potency on oral administration.
Chemical ID: MESH:D004997
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Serping1affects expressionEXP 6480464CTDEthinyl Estradiol affects the expression of SERPING1 mRNA

PMID:16079270
Serping1decreases expressionEXP 6480464CTDEthinyl Estradiol results in decreased expression of SERPING1 mRNA

PMID:15576828
Serping1affects expressionISORGD:15528056480464CTDEthinyl Estradiol affects the expression of SERPING1 mRNA

PMID:17555576
Serping1increases expressionISORGD:15528056480464CTDEthinyl Estradiol results in increased expression of SERPING1 mRNA

PMID:17942748
Serping1multiple interactionsISORGD:15528056480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of SERPING1 mRNA

PMID:17942748
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.