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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733175
Species: Mus musculus
RGD Object: Gene
Symbol: S100a9
Name: S100 calcium binding protein A9 (calgranulin B)
Acc ID: CHEBI:4903
Term: 17alpha-ethynylestradiol
Definition: A 3-hydroxy steroid that is estradiol substituted by a ethynyl group at position 17. It is a xenoestrogen synthesized from estradiol and has been shown to exhibit high estrogenic potency on oral administration.
Chemical ID: MESH:D004997
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
S100a9affects expressionEXP 6480464CTDEthinyl Estradiol affects the expression of S100A9 mRNAPMID:17555576
S100a9multiple interactionsEXP 6480464CTDEthinyl Estradiol promotes the reaction [IL1B protein results in increased expression of S100A9 mRNA]PMID:12072388
S100a9increases expressionISOS100a9 (Rattus norvegicus)6480464CTDEthinyl Estradiol results in increased expression of S100A9 mRNAPMID:15901920
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