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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732911
Species: Mus musculus
RGD Object: Gene
Symbol: Cdkn1a
Name: cyclin dependent kinase inhibitor 1A
Acc ID: CHEBI:4903
Term: 17alpha-ethynylestradiol
Definition: A 3-hydroxy steroid that is estradiol substituted by a ethynyl group at position 17. It is a xenoestrogen synthesized from estradiol and has been shown to exhibit high estrogenic potency on oral administration.
Chemical ID: MESH:D004997
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdkn1aaffects expressionEXP 6480464CTDEthinyl Estradiol affects the expression of CDKN1A mRNAPMID:14976129
Cdkn1aincreases expressionEXP 6480464CTDEthinyl Estradiol results in increased expression of CDKN1A mRNAPMID:17555576 PMID:17942748
Cdkn1amultiple interactionsEXP 6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CDKN1A mRNAPMID:17942748
Cdkn1aaffects expressionISOCdkn1a (Rattus norvegicus)6480464CTDEthinyl Estradiol affects the expression of CDKN1A mRNAPMID:26865667
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