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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3738
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sp1
Name: Sp1 transcription factor
Acc ID: CHEBI:490095
Term: esculetin
Definition: A hydroxycoumarin that is umbelliferone in which the hydrogen at position 6 is substituted by a hydroxy group. It is used in filters for absorption of ultraviolet light.
Chemical ID: MESH:C007628
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sp1decreases expressionISOSP1 (Homo sapiens)6480464CTDesculetin results in decreased expression of SP1 proteinPMID:31313495
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