Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:490095
Term: esculetin
Definition: A hydroxycoumarin that is umbelliferone in which the hydrogen at position 6 is substituted by a hydroxy group. It is used in filters for absorption of ultraviolet light.
Chemical ID: MESH:C007628
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxaffects expressionISOBAX (Homo sapiens)6480464CTDesculetin affects the expression of BAX proteinPMID:24995577
Baxaffects localizationISOBAX (Homo sapiens)6480464CTDesculetin affects the localization of BAX proteinPMID:19786087
Baxincreases expressionISOBAX (Homo sapiens)6480464CTDesculetin results in increased expression of BAX proteinPMID:26388407 PMID:31313495
Baxmultiple interactionsISOBAX (Homo sapiens)6480464CTD[esculetin co-treated with Paclitaxel] results in increased expression of BAX proteinPMID:16051289
Go Back to source page   Continue to Ontology report