Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   


RGD ID: 69408
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lcn2
Name: lipocalin 2
Acc ID: CHEBI:49005
Term: deferasirox
Definition: A member of the class of triazoles, deferasirox is 1,2,4-triazole substituted by a 4-carboxyphenyl group at position 1 and by 2-hydroxyphenyl groups at positions 3 and 5. An orally active iron chelator, it is used to manage chronic iron overload in patients receiving long-term blood transfusions.
Chemical ID: MESH:C415250
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lcn2increases expressionEXP 6480464CTDdeferasirox results in increased expression of LCN2 proteinPMID:21439361
Lcn2increases expressionISORGD:694546480464CTDdeferasirox results in increased expression of LCN2 proteinPMID:21439361
Go Back to source page   Continue to Ontology report