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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10787
Species: Mus musculus
RGD Object: Gene
Symbol: Il17a
Name: interleukin 17A
Acc ID: CHEBI:49
Term: (+)-Tetrandrine
Definition: A bisbenzylisoquinoline alkaloid that has formula C38H42N2O6.
Chemical ID: MESH:C009438
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il17adecreases expressionEXP 6480464CTDtetrandrine results in decreased expression of IL17A mRNAPMID:26640276
Il17amultiple interactionsEXP 6480464CTDresveratrol inhibits the reaction [tetrandrine inhibits the reaction [COL2A1 protein results in increased expression of IL17A protein]]; tetrandrine inhibits the reaction [COL2A1 protein results in increased expression of IL17A protein]PMID:26640276
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