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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730846
Species: Homo sapiens
RGD Object: Gene
Symbol: CASP8
Name: caspase 8
Acc ID: CHEBI:48965
Term: trans-chalcone
Definition: The trans-isomer of chalcone.
Chemical ID: MESH:D002599
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CASP8increases cleavageEXP 6480464CTDChalcone results in increased cleavage of CASP8 proteinPMID:20620131
CASP8multiple interactionsEXP 6480464CTDMYC protein affects the susceptibility to [Chalcone results in increased cleavage of CASP8 protein]PMID:20620131
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