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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735753
Species: Mus musculus
RGD Object: Gene
Symbol: Runx2
Name: runt related transcription factor 2
Acc ID: CHEBI:48861
Term: 2-trans,6-trans,10-trans-geranylgeranyl diphosphate
Definition: The all-trans-isomer of geranylgeranyl diphosphate.
Chemical ID: MESH:C002963
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Runx2multiple interactionsEXP 6480464CTDgeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]]PMID:18310456
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