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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:48843
Term: disodium selenite
Definition: An inorganic sodium salt composed of sodium and selenite ions in a 2:1 ratio.
Chemical ID: MESH:D018038
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxdecreases expressionEXP 6480464CTDSodium Selenite results in decreased expression of BAX proteinPMID:18209489
Baxmultiple interactionsEXP 6480464CTDSodium Selenite inhibits the reaction [2-cresol results in increased expression of BAX mRNA]; Sodium Selenite inhibits the reaction [citreoviridin results in increased expression of BAX protein]PMID:21705299 PMID:31419397
Baxincreases expressionISOBax (Mus musculus)6480464CTDSodium Selenite results in increased expression of BAX mRNAPMID:16542727
Baxincreases expressionISOBAX (Homo sapiens)6480464CTDSodium Selenite results in increased expression of BAX mRNA; Sodium Selenite results in increased expression of BAX proteinPMID:16705456 PMID:34520753
Baxmultiple interactionsISOBax (Mus musculus)6480464CTDSodium Selenite inhibits the reaction [citreoviridin results in increased expression of BAX protein]PMID:31419397
Baxmultiple interactionsISOBAX (Homo sapiens)6480464CTD[Sodium Selenite co-treated with (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane] results in increased expression of BAX proteinPMID:28757135
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