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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732911
Species: Mus musculus
RGD Object: Gene
Symbol: Cdkn1a
Name: cyclin dependent kinase inhibitor 1A
Acc ID: CHEBI:48765
Term: dimethylarsinic acid
Definition: The organoarsenic compound that is arsenic acid substituted on the central arsenic atom with two methyl groups.
Chemical ID: MESH:D002101
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdkn1adecreases expressionISOCdkn1a (Rattus norvegicus)6480464CTDCacodylic Acid results in decreased expression of CDKN1A mRNA; Cacodylic Acid results in decreased expression of CDKN1A proteinPMID:12151359 PMID:17481689
Cdkn1amultiple interactionsISOCDKN1A (Homo sapiens)6480464CTD[sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of CDKN1A mRNAPMID:23192986
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