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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628627
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2b3
Name: cytochrome P450, family 2, subfamily b, polypeptide 3
Acc ID: CHEBI:48722
Term: 2-nitroanisole
Definition: A member of the class of 2-nitroanisoles that is anisole in which one of the hydrogens ortho to the methoxy group is replaced by a nitro group.
Chemical ID: MESH:C005328
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2b3increases metabolic processingISORGD:13467516480464CTDCYP2B6 protein results in increased metabolism of 2-nitroanisole

PMID:15144223
Cyp2b3increases oxidationISORGD:13467516480464CTDCYP2B6 protein results in increased oxidation of 2-nitroanisole

PMID:17159769, PMID:21218109
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.