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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730901
Species: Homo sapiens
RGD Object: Gene
Symbol: HMOX1
Name: heme oxygenase 1
Acc ID: CHEBI:48607
Term: lithium chloride
Definition: A metal chloride salt with a Li(+) counterion.
Chemical ID: MESH:D018021
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HMOX1increases expressionEXP 6480464CTDLithium Chloride results in increased expression of HMOX1 mRNAPMID:23527032
HMOX1multiple interactionsEXP 6480464CTD[Lithium Chloride results in increased abundance of Lithium] which results in increased expression of HMOX1 mRNA; Lithium Chloride promotes the reaction [Sesquiterpenes analog results in increased expression of HMOX1 protein]PMID:26074776 PMID:30672058
HMOX1multiple interactionsISOHmox1 (Rattus norvegicus)6480464CTDLithium Chloride affects the reaction [[gastrodin co-treated with rhyncophylline] affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of HMOX1 protein]]; Lithium Chloride inhibits the reaction [Matrines results in decreased expression of HMOX1 protein]; Lithium Chloride promotes the reaction [Cadmium results in increased expression of HMOX1 protein]PMID:27658547 PMID:33645131 PMID:37075934
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