GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bcl2 | multiple interactions | EXP | | 6480464 | CTD | Lithium Chloride inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]; Lithium Chloride inhibits the reaction [Etoposide results in decreased expression of BCL2 mRNA]; Lithium Chloride inhibits the reaction [Etoposide results in decreased expression of BCL2 protein]; Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of BCL2 protein] | PMID:19408126 PMID:30171970 PMID:31220555 | Bcl2 | increases expression | ISO | Bcl2 (Rattus norvegicus) | 6480464 | CTD | Lithium Chloride results in increased expression of BCL2 mRNA | PMID:17404573 | Bcl2 | increases expression | ISO | BCL2 (Homo sapiens) | 6480464 | CTD | Lithium Chloride results in increased expression of BCL2 mRNA; Lithium Chloride results in increased expression of BCL2 protein | PMID:18830594 PMID:19101580 | Bcl2 | multiple interactions | ISO | Bcl2 (Rattus norvegicus) | 6480464 | CTD | Lithium Chloride inhibits the reaction [citronellal inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]]; Lithium Chloride inhibits the reaction [Matrines results in decreased expression of BCL2 protein]; Lithium Chloride inhibits the reaction [triptolide results in decreased expression of BCL2 protein] | PMID:30926361 PMID:34813134 PMID:37075934 | Bcl2 | multiple interactions | ISO | BCL2 (Homo sapiens) | 6480464 | CTD | [Lithium Chloride results in increased abundance of Lithium] promotes the reaction [Paraquat results in increased expression of BCL2 mRNA]; [Lithium Chloride results in increased abundance of Lithium] which results in increased expression of BCL2 mRNA; [Lithium Chloride results in increased abundance of Lithium] which results in increased expression of BCL2 protein; [Paraquat co-treated with [Lithium Chloride results in increased abundance of Lithium]] results in increased expression of BCL2 protein | PMID:26074776 | | ||||||||||||||||||||||
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