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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1558284
Species: Mus musculus
RGD Object: Gene
Symbol: Ugt1a2
Name: UDP glucuronosyltransferase 1 family, polypeptide A2
Acc ID: CHEBI:48574
Term: phenylbutazone
Definition: A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.
Chemical ID: MESH:D010653
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ugt1a2multiple interactionsISOUGT1A3 (Homo sapiens)6480464CTDPhenylbutazone inhibits the reaction [UGT1A3 protein results in increased glucuronidation of Diethylstilbestrol]PMID:23126256
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