GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Drd2 | affects response to substance | EXP | | 6480464 | CTD | DRD2 protein affects the susceptibility to Apomorphine | PMID:14639100 PMID:2571179 PMID:8103596 | Drd2 | multiple interactions | EXP | | 6480464 | CTD | Risperidone inhibits the reaction [Apomorphine binds to and results in increased activity of DRD2 protein] | PMID:7520908 | Drd2 | increases response to substance | ISO | Drd2 (Mus musculus) | 6480464 | CTD | DRD2 protein results in increased susceptibility to Apomorphine | PMID:19497322 | Drd2 | multiple interactions | ISO | Drd2 (Mus musculus) | 6480464 | CTD | [[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole; Raclopride inhibits the reaction [[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole]; SCH 23390 inhibits the reaction [[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole] | PMID:8103921 | |
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