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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69267
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc5a5
Name: solute carrier family 5 member 5
Acc ID: CHEBI:48347
Term: triclocarban
Definition: A member of the class of phenylureas that is urea substituted by a 4-chlorophenyl group and a 3,4-dichlorophenyl group at positions 1 and 3 respectively.
Chemical ID: MESH:C009540
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc5a5decreases activityEXP 6480464CTDtriclocarban results in decreased activity of SLC5A5 protein

PMID:26827900
Slc5a5multiple interactionsISORGD:7317516480464CTDtriclocarban inhibits the reaction [SLC5A5 protein results in increased uptake of Iodine]

PMID:27979590
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