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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2147
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ar
Name: androgen receptor
Acc ID: CHEBI:48347
Term: triclocarban
Definition: A member of the class of phenylureas that is urea substituted by a 4-chlorophenyl group and a 3,4-dichlorophenyl group at positions 1 and 3 respectively.
Chemical ID: MESH:C009540
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Armultiple interactionsISORGD:7356526480464CTDtriclocarban analog promotes the reaction [Testosterone results in increased activity of AR protein] triclocarban promotes the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein] triclocarban promotes the reaction [Testosterone results in increased activity of AR protein] triclocarban promotes the reaction [Trenbolone Acetate results in increased activity of AR protein]

PMID:18795164 PMID:20821581 PMID:20943248
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