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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736217
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP2D6
Name: cytochrome P450 family 2 subfamily D member 6
Acc ID: CHEBI:48286
Term: N,N-diisopropyltryptamine
Definition: A tryptamine that has formula C16H24N2.
Chemical ID: MESH:C033695
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP2D6decreases activityEXP 6480464CTDN,N-diisopropyltryptamine analog results in decreased activity of CYP2D6 proteinPMID:26599973
CYP2D6multiple interactionsEXP 6480464CTD[N,N-diisopropyltryptamine analog results in decreased activity of CYP2D6 protein] which results in decreased metabolism of DextromethorphanPMID:26599973
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