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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3249
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Serpine1
Name: serpin family E member 1
Acc ID: CHEBI:48131
Term: nonanedioic acid
Definition: An alpha,omega-dicarboxylic acid that is heptane substituted at positions 1 and 7 by carboxy groups.
Chemical ID: MESH:C010038
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Serpine1increases expressionISORGD:690146480464CTDazelaic acid results in increased expression of SERPINE1 mRNA

PMID:8635147
Serpine1multiple interactionsISORGD:690146480464CTDazelaic acid results in increased expression of and results in increased secretion of SERPINE1 protein

PMID:8635147
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.