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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1564975
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dct
Name: dopachrome tautomerase
Acc ID: CHEBI:48131
Term: nonanedioic acid
Definition: An alpha,omega-dicarboxylic acid that is heptane substituted at positions 1 and 7 by carboxy groups.
Chemical ID: MESH:C010038
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dctdecreases expressionISORGD:15574066480464CTDazelaic acid results in decreased expression of DCT protein

PMID:20804622
Dctmultiple interactionsISORGD:15574066480464CTD[Taurine co-treated with azelaic acid] results in decreased expression of DCT protein

PMID:20804622
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.