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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621758
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp12
Name: caspase 12
Acc ID: CHEBI:48080
Term: brefeldin A
Definition: A metabolite from Penicillium brefeldianum that exhibits a wide range of antibiotic activity.
Chemical ID: MESH:D020126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases activityISORGD:7314426480464CTDBrefeldin A results in increased activity of CASP12 protein

PMID:20493918
multiple interactionsISORGD:7314426480464CTDApigenin inhibits the reaction [Brefeldin A results in increased activity of CASP12 protein]

PMID:20493918
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.