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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1551988
Species: Mus musculus
RGD Object: Gene
Symbol: Parp1
Name: poly (ADP-ribose) polymerase family, member 1
Acc ID: CHEBI:48080
Term: brefeldin A
Definition: A metabolite from Penicillium brefeldianum that exhibits a wide range of antibiotic activity.
Chemical ID: MESH:D020126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Parp1increases cleavageEXP 6480464CTDBrefeldin A results in increased cleavage of PARP1 proteinPMID:20493918
Parp1multiple interactionsEXP 6480464CTDApigenin inhibits the reaction [Brefeldin A results in increased cleavage of PARP1 protein]PMID:20493918
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