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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10289
Species: Mus musculus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:48080
Term: brefeldin A
Definition: A metabolite from Penicillium brefeldianum that exhibits a wide range of antibiotic activity.
Chemical ID: MESH:D020126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3increases activityEXP 6480464CTDBrefeldin A results in increased activity of CASP3 proteinPMID:20493918
Casp3multiple interactionsEXP 6480464CTDApigenin inhibits the reaction [Brefeldin A results in increased activity of CASP3 protein]PMID:20493918
Casp3increases activityISOCASP3 (Homo sapiens)6480464CTDBrefeldin A results in increased activity of CASP3 proteinPMID:20150630
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