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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70496
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk14
Name: mitogen activated protein kinase 14
Acc ID: CHEBI:4806
Term: (-)-epigallocatechin 3-gallate
Definition: A gallate ester obtained by the formal condensation of gallic acid with the (3R)-hydroxy group of (-)-epigallocatechin.
Chemical ID: MESH:C045651
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk14increases expressionISOMAPK14 (Homo sapiens)6480464CTDepigallocatechin gallate results in increased expression of MAPK14 mRNAPMID:35701726
Mapk14multiple interactionsISOMAPK14 (Homo sapiens)6480464CTD[epigallocatechin gallate co-treated with Celecoxib] results in increased activity of MAPK14 protein; [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of MAPK14 mRNAPMID:16463383 PMID:22079256
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