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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2943
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Jun
Name: Jun proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:4806
Term: (-)-epigallocatechin 3-gallate
Definition: A gallate ester obtained by the formal condensation of gallic acid with the (3R)-hydroxy group of (-)-epigallocatechin.
Chemical ID: MESH:C045651
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Junincreases expressionISOJUN (Homo sapiens)6480464CTDepigallocatechin gallate results in increased expression of JUN proteinPMID:12663506
Junmultiple interactionsISOJUN (Homo sapiens)6480464CTDepigallocatechin gallate inhibits the reaction [Particulate Matter results in increased phosphorylation of JUN protein]PMID:31252129
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