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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1332548
Species: Mus musculus
RGD Object: Gene
Symbol: Ppargc1a
Name: peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
Acc ID: CHEBI:4806
Term: (-)-epigallocatechin 3-gallate
Definition: A gallate ester obtained by the formal condensation of gallic acid with the (3R)-hydroxy group of (-)-epigallocatechin.
Chemical ID: MESH:C045651
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppargc1adecreases expressionEXP 6480464CTDepigallocatechin gallate results in decreased expression of PPARGC1A proteinPMID:29175576
Ppargc1amultiple interactionsISOPpargc1a (Rattus norvegicus)6480464CTD[1-Methyl-4-phenylpyridinium co-treated with epigallocatechin gallate] results in increased expression of PPARGC1A mRNA; [1-Methyl-4-phenylpyridinium co-treated with epigallocatechin gallate] results in increased expression of PPARGC1A proteinPMID:22742579
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