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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10789
Species: Mus musculus
RGD Object: Gene
Symbol: Il1a
Name: interleukin 1 alpha
Acc ID: CHEBI:4806
Term: (-)-epigallocatechin 3-gallate
Definition: A gallate ester obtained by the formal condensation of gallic acid with the (3R)-hydroxy group of (-)-epigallocatechin.
Chemical ID: MESH:C045651
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1amultiple interactionsEXP 6480464CTDepigallocatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]PMID:7665919
Il1adecreases expressionISOIL1A (Homo sapiens)6480464CTDepigallocatechin gallate results in decreased expression of IL1A mRNAPMID:20706672
Il1amultiple interactionsISOIL1A (Homo sapiens)6480464CTD[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of IL1A mRNAPMID:22079256
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