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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2139
Species: Rattus norvegicus
RGD Object: Gene
Symbol: App
Name: amyloid beta precursor protein
Acc ID: CHEBI:48058
Term: buten-2-one
Definition: A methyl ketone that is butan-2-one with an unsaturation at position 3.
Chemical ID: MESH:C057920
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Appmultiple interactionsISORGD:7360216480464CTD[3-buten-2-one results in increased metabolism of APP protein] which results in increased secretion of APP protein modified form

PMID:29618714
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.