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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1350750
Species: Homo sapiens
RGD Object: Gene
Symbol: SLCO1B3
Name: solute carrier organic anion transporter family member 1B3
Acc ID: CHEBI:48041
Term: microcystin
Definition: A family of cyclic heptapeptide hepatotoxins produced by a number of cyanobacteria, the most notable of which is Microcystis, from which the name of the family is derived. Microcystins consist of a heptapeptide macrocycle made up of five non-protein amino acids and two protein amino acids.
Chemical ID: MESH:D052998
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SLCO1B3increases uptakeEXP 6480464CTDSLCO1B3 protein results in increased uptake of MicrocystinsPMID:20472527
SLCO1B3increases uptakeISOSlco1b2 (Mus musculus)6480464CTDSLCO1B2 protein results in increased uptake of MicrocystinsPMID:20472527
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