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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737121
Species: Mus musculus
RGD Object: Gene
Symbol: Ccn5
Name: cellular communication network factor 5
Acc ID: CHEBI:4791
Term: endosulfan
Definition: A cyclic sulfite ester that is 1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepine 3-oxide substituted by chloro groups at positions 6, 7, 8, 9, 10 and 10.
Chemical ID: MESH:D004726
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:6218676480464CTDEndosulfan results in decreased expression of CCN5 mRNA

PMID:29391264
increases expressionISORGD:13514966480464CTDEndosulfan results in increased expression of CCN5 mRNA

PMID:23384675
multiple interactionsISORGD:13514966480464CTDESR1 protein inhibits the reaction [Endosulfan results in increased expression of CCN5 mRNA]

PMID:23384675
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.