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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733705
Species: Homo sapiens
RGD Object: Gene
Symbol: CTNNB1
Name: catenin beta 1
Acc ID: CHEBI:4791
Term: endosulfan
Definition: A cyclic sulfite ester that is 1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepine 3-oxide substituted by chloro groups at positions 6, 7, 8, 9, 10 and 10.
Chemical ID: MESH:D004726
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CTNNB1decreases expressionEXP 6480464CTDEndosulfan results in decreased expression of CTNNB1 proteinPMID:28108160
CTNNB1multiple interactionsEXP 6480464CTDEndosulfan inhibits the reaction [CDH1 protein binds to CTNNB1 protein]; Endosulfan results in increased expression of and affects the localization of CTNNB1 proteinPMID:22677888 PMID:22902829
CTNNB1affects expressionISOCtnnb1 (Rattus norvegicus)6480464CTDEndosulfan affects the expression of CTNNB1 proteinPMID:26911934
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