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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2218
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Brca1
Name: BRCA1, DNA repair associated
Acc ID: CHEBI:4791
Term: endosulfan
Definition: A cyclic sulfite ester that is 1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepine 3-oxide substituted by chloro groups at positions 6, 7, 8, 9, 10 and 10.
Chemical ID: MESH:D004726
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Brca1affects expressionISOBRCA1 (Homo sapiens)6480464CTDEndosulfan affects the expression of BRCA1 mRNAPMID:29705383
Brca1multiple interactionsISOBRCA1 (Homo sapiens)6480464CTD2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Endosulfan affects the expression of BRCA1 mRNA]PMID:29705383
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