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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733290
Species: Mus musculus
RGD Object: Gene
Symbol: Akr1c18
Name: aldo-keto reductase family 1, member C18
Acc ID: CHEBI:47807
Term: sulforaphane
Definition: An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
Chemical ID: MESH:C016766
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akr1c18increases expressionISOAKR1C3 (Homo sapiens)6480464CTDsulforaphane results in increased expression of AKR1C3 mRNA; sulforaphane results in increased expression of AKR1C3 proteinPMID:24383545 PMID:31746589
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