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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733073
Species: Mus musculus
RGD Object: Gene
Symbol: Slc40a1
Name: solute carrier family 40 (iron-regulated transporter), member 1
Acc ID: CHEBI:47807
Term: sulforaphane
Definition: An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
Chemical ID: MESH:C016766
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc40a1increases expressionEXP 6480464CTDsulforaphane results in increased expression of SLC40A1 proteinPMID:32416107
Slc40a1multiple interactionsEXP 6480464CTDsulforaphane inhibits the reaction [Busulfan results in decreased expression of SLC40A1 protein]; sulforaphane inhibits the reaction [Lipopolysaccharides results in decreased expression of SLC40A1 mRNA]PMID:21303654 PMID:32416107
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