GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ahr | multiple interactions | EXP | | 6480464 | CTD | sulforaphane inhibits the reaction [Benzo(a)pyrene results in increased activity of AHR protein] | PMID:21177068 | Ahr | affects binding | ISO | Ahr (Rattus norvegicus) | 6480464 | CTD | sulforaphane binds to AHR protein | PMID:23566952 | Ahr | multiple interactions | ISO | Ahr (Rattus norvegicus) | 6480464 | CTD | [sulforaphane analog inhibits the reaction [Benzo(a)pyrene binds to AHR protein]] promotes the reaction [sulforaphane analog binds to AHR protein]; sulforaphane analog inhibits the reaction [Benzo(a)pyrene binds to AHR protein] | PMID:22643862 | Ahr | multiple interactions | ISO | AHR (Homo sapiens) | 6480464 | CTD | AHR mutant form inhibits the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]]; AHR mutant form inhibits the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]]; AHR mutant form inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]]; AHR mutant form inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]]; sulforaphane affects the reaction [anthracene affects the localization of AHR protein]; sulforaphane inhibits the reaction [1,2,5,6-dibenzanthracene affects the localization of AHR protein]; sulforaphane inhibits the reaction [Benzo(a)pyrene affects the localization of AHR protein] | PMID:19202560 PMID:19362136 PMID:23583297 | | ||||||||||||||||||||||
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