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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61813
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ftl1
Name: ferritin light chain 1
Acc ID: CHEBI:4776
Term: ellipticine
Definition: A organic heterotetracyclic compound that is pyrido[4,3-b]carbazole carrying two methyl substituents at positions 5 and 11.
Chemical ID: MESH:C034192
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ftl1multiple interactionsISOFTL (Homo sapiens)6480464CTD[ellipticine binds to FTL protein] which results in increased expression of H2AX protein modified form; FTL protein binds to and results in decreased uptake of ellipticinePMID:30914192
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