GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Trp53 | increases expression | ISO | TP53 (Homo sapiens) | 6480464 | CTD | ellipticine results in increased expression of TP53 protein | PMID:29471073 | Trp53 | increases response to substance | ISO | TP53 (Homo sapiens) | 6480464 | CTD | TP53 protein results in increased susceptibility to ellipticine | PMID:29471073 | Trp53 | multiple interactions | ISO | TP53 (Homo sapiens) | 6480464 | CTD | TP53 protein promotes the reaction [[ellipticine results in increased susceptibility to Benzo(a)pyrene] which results in increased expression of CDKN1A protein]; TP53 protein promotes the reaction [ellipticine inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]]; TP53 protein promotes the reaction [ellipticine results in increased expression of CDKN1A protein]; TP53 protein promotes the reaction [ellipticine results in increased expression of CYP1A1 protein] | PMID:29471073 | | ||||||||||||||||||||||
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