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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2366
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc2
Name: ATP binding cassette subfamily C member 2
Acc ID: CHEBI:47612
Term: bezafibrate
Definition: A monocarboxylic acid amide obtained by the formal condensation of the carboxy group of 4-chlorobenzoic acid with the amino group of 2-[4-(2-aminoethyl)phenoxy]-2-methylpropanoic acid. Benafibrate is used for the treatment of hyperlipidaemia.
Chemical ID: MESH:D001629
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc2affects localizationISOABCC2 (Homo sapiens)6480464CTDBezafibrate affects the localization of ABCC2 proteinPMID:15258199
Abcc2increases expressionISOABCC2 (Homo sapiens)6480464CTDBezafibrate results in increased expression of ABCC2 mRNAPMID:15258199
Abcc2multiple interactionsISOAbcc2 (Mus musculus)6480464CTD[Sodium Glutamate co-treated with Bezafibrate] results in increased expression of ABCC2 mRNAPMID:21549692
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