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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1317785
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp2c65
Name: cytochrome P450, family 2, subfamily c, polypeptide 65
Acc ID: CHEBI:4754
Term: econazole
Definition: A racemate composed of equimolar amounts of (R)- and (S)-econazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections.
Chemical ID: MESH:D004464
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2c65multiple interactionsISOCYP2C9 (Homo sapiens)6480464CTDEconazole binds to and results in decreased activity of CYP2C9 protein; Econazole binds to and results in decreased activity of CYP2C9 protein alternative formPMID:29621561
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