GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Prkn | increases expression | ISO | Prkn (Rattus norvegicus) | 6480464 | CTD | Ketoconazole results in increased expression of PRKN mRNA; Ketoconazole results in increased expression of PRKN protein | PMID:25787151 | Prkn | increases response to substance | ISO | Prkn (Rattus norvegicus) | 6480464 | CTD | PRKN protein results in increased susceptibility to Ketoconazole | PMID:25787151 | Prkn | multiple interactions | ISO | Prkn (Rattus norvegicus) | 6480464 | CTD | 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Ketoconazole results in increased expression of PRKN mRNA]; 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Ketoconazole results in increased expression of PRKN protein]; tempol inhibits the reaction [Ketoconazole results in increased expression of PRKN mRNA]; tempol inhibits the reaction [Ketoconazole results in increased expression of PRKN protein] | PMID:25787151 | | ||||||||||||||||||||||
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