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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70970
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hmgcs1
Name: 3-hydroxy-3-methylglutaryl-CoA synthase 1
Acc ID: CHEBI:47499
Term: imipramine
Definition: A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Chemical ID: MESH:D007099
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hmgcs1increases expressionISOHMGCS1 (Homo sapiens)6480464CTDImipramine results in increased expression of HMGCS1 mRNAPMID:16324787
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