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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68584
Species: Homo sapiens
RGD Object: Gene
Symbol: KCNH1
Name: potassium voltage-gated channel subfamily H member 1
Acc ID: CHEBI:47499
Term: imipramine
Definition: A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Chemical ID: MESH:D007099
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDImipramine binds to and results in decreased activity of KCNH1 protein

PMID:18497958
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.