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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:47381
Term: diclofenac
Definition: A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Chemical ID: MESH:D004008
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxincreases expressionEXP 6480464CTDDiclofenac results in increased expression of BAX mRNAPMID:29027214
Baxaffects localizationISOBAX (Homo sapiens)6480464CTDDiclofenac affects the localization of BAX proteinPMID:18191430
Baxincreases activityISOBAX (Homo sapiens)6480464CTDDiclofenac results in increased activity of BAX proteinPMID:18191430
Baxincreases expressionISOBAX (Homo sapiens)6480464CTDDiclofenac results in increased expression of BAX mRNAPMID:29027214
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