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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10510
Species: Mus musculus
RGD Object: Gene
Symbol: Egf
Name: epidermal growth factor
Acc ID: CHEBI:47318
Term: 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime
Definition: An imidazothiazole that has formula C19H12Cl3N3OS.
Chemical ID: MESH:C475093
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7368326480464CTD6-(4-chlorophenyl)imidazo(2, 1-b)(1, 3)thiazole-5-carbaldehyde O-(3, 4-dichlorobenzyl)oxime inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]

PMID:25625231, PMID:30364229
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.