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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1347389
Species: Homo sapiens
RGD Object: Gene
Symbol: MIR29B1
Name: microRNA 29b-1
Acc ID: CHEBI:472805
Term: ouabain
Definition: A steroid hormone that is a multi-hydroxylated alpha-L-rhamnosyl cardenoloide. It binds to and inhibits the plasma membrane Na(+)/K(+)-ATPase (sodium pump). It has been isolated naturally from Strophanthus gratus.
Chemical ID: MESH:D010042
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MIR29B1decreases expressionISOMir29b1 (Rattus norvegicus)6480464CTDOuabain results in decreased expression of MIR29B1 mRNAPMID:26702050
MIR29B1multiple interactionsISOMir29b1 (Rattus norvegicus)6480464CTDMIR29B1 mRNA inhibits the reaction [Ouabain results in increased expression of COL1A1 mRNA]PMID:26702050
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