Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737039
Species: Homo sapiens
RGD Object: Gene
Symbol: CDKN2A
Name: cyclin dependent kinase inhibitor 2A
Acc ID: CHEBI:47217
Term: arsane
Definition: An arsine that has formula 77.94542.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CDKN2Aaffects expressionEXP 6480464CTDArsenic affects the expression of CDKN2A proteinPMID:17450239
CDKN2Adecreases expressionEXP 6480464CTDArsenic results in decreased expression of CDKN2A mRNAPMID:23872714
CDKN2Aincreases expressionEXP 6480464CTDArsenic results in increased expression of CDKN2A mRNAPMID:12773770
CDKN2Aincreases methylationEXP 6480464CTDArsenic results in increased methylation of CDKN2A gene; Arsenic results in increased methylation of CDKN2A promoter; Arsenic results in increased methylation of CDKN2A promoter alternative formPMID:16251483 PMID:22466225 PMID:23073540 PMID:23872714 PMID:24525453 PMID:25598836
CDKN2Adecreases expressionISOCdkn2a (Mus musculus)6480464CTDArsenic results in decreased expression of CDKN2A mRNA; Arsenic results in decreased expression of CDKN2A proteinPMID:22843710
CDKN2Amultiple interactionsISOCdkn2a (Mus musculus)6480464CTDBMI1 protein promotes the reaction [Arsenic results in decreased expression of CDKN2A mRNA]; BMI1 protein promotes the reaction [Arsenic results in decreased expression of CDKN2A protein]; SUZ12 protein promotes the reaction [Arsenic results in decreased expression of CDKN2A mRNA]; SUZ12 protein promotes the reaction [Arsenic results in decreased expression of CDKN2A protein]PMID:22843710
Go Back to source page   Continue to Ontology report